Plasma Fatty Acid Binding Protein 4 and Risk of Sudden Cardiac Death in Older Adults

Table 4

Hazard ratio (95% CI) of SCD per each SD (18.98 ng/mL) increase of FABP4 concentration, by diabetes status (𝑛=4483).

	Diabetics (𝑛=682)		Nondiabetics (𝑛=3801)
	HR (95% CI)	𝑃 value	HR (95% CI)	𝑃 value	𝑃 interaction†
Model 1*	0.95 (0.70–1.28)	0.72	1.45 (1.26–1.67)	<0.0001	0.056
Model 2**	0.81 (0.56–1.17)	0.26	1.35 (1.10–1.65)	0.004	0.050
Model 3***	0.88 (0.62–1.27)	0.50	1.33 (1.07–1.65)	0.009	0.049

∗Model 1: adjusted for age, sex, race, and field center.
∗∗Model 2: adjusted for variables in model 1 plus GFR-cystatin, hsCRP (log transformed), kcal of leisure time physical activity (log transformed), hormone replacement therapy, alcohol, health status, and smoking.
∗∗Model 3: adjusted for variables in model 2 plus body mass index.
†Interaction between diabetes status and FABP4.
There were 41 SCDs in diabetic participants and 102 SCDs events in non-diabetic participants.