Clinical Study

Patterns of Change in Cognitive Function over Six Months in Adults with Chronic Heart Failure

Table 3

Factors predicting below average processing speed: unadjusted and adjusted odds.

Unadjusted odds ratio (95% CI) valueAdjusted  odds ratio (95% CI) value

Age1.08 (1.06–1.11)<.0011.12 (1.08–1.16)<.001
Female0.48 (0.30–0.81).0050.42 (0.21–0.85).016
Non-Caucasian2.62 (1.55–4.43)<.0012.82 (1.21–6.55).016
ANART-FSIQ0.61 (0.50–0.74)<.0010.75 (0.54–1.03).078
Ejection fraction1.01 (0.99–1.02).4101.02 (1.00–1.05).033
Income1.43 (1.01–2.04).0461.41 (0.83–2.41).208
Charlson moderate*2.47 (1.45–4.19).0011.81 (0.90–3.64).096
Charlson high*10.30 (2.99–35.45)<.0019.65 (1.77–52.54).009
ACE inhibitor0.57 (0.35–0.93).0240.67 (0.23–1.34).259
Beta blocker0.71 (0.28–1.81).4671.55 (0.38–6.41).543
Years of education0.80 (0.73–0.88)<.0010.85 (0.74–0.98).024
Mean arterial pressure0.99 (0.99–1.00).2960.99 (0.99–1.01).179
NYHA1.38 (0.99–1.92).0560.85 (0.52–1.38).506
Excessive daytime sleepiness1.39 (0.79–2.48).2572.42 (1.05–5.53).037
BMI1.05 (1.01–1.08).0071.06 (1.01–1.11).009
Basel adherence score0.84 (0.65–1.09).1921.06 (0.61–1.22).402
Exercise minimal1.11 (0.56–2.21).7680.92 (0.35–2.44).865
Exercise adequate0.44 (0.23–0.86).0160.61 (0.24–1.58).313

*Relative to low Charlson comorbid category.
Relative to no exercise.
Key: ANART: American National Adult Reading Test; ACE Inhibitor: angiotensin converting enzyme inhibitor; NYHA: New York Heart Association.