Review Article

Review of Cardiotoxicity in Pediatric Cancer Patients: During and after Therapy

Table 2

Timing of echocardiograms or MUGA scan postcancer therapy as per children’s oncology group long-term followup guidelines for survivors of childhood, adolescent, and young adult cancers version 3.0 [82].

Age at treatmentRadiation with potential impact to the heartAnthracycline dose converted to doxorubicin isotoxic doseRecommended frequency

<1 year oldYesAnyEvery year
No<200 mg/m2Every 2 years
≥200 mg/m2Every year

1–4 years oldYesAnyEvery year
No<100 mg/m2Every 5 years
≥100 to <300 mg/m2Every 2 years
≥300 mg/m2Every year

≥5 years old Yes<300 mg/m2Every 2 years
≥300 mg/m2Every year
No<200 mg/m2Every 5 years
≥200 mg/m2 to <300 mg/m2Every 2 years
≥300 mg/m2Every year
Any age with decrease in serial functionEvery year