Contribution of CT Features in the Diagnosis of COVID-19

Table 1

The positive rate/sensitivity and specificity of initial RT-PCR and initial CT based on the published studies.

	Biological sample	Reference standard	Initial RT-PCR PT/Sen	Initial RT-PCR Spe	Initial CT PT/Sen	Initial CT Spe
Li et al. [14]	Pharyngeal swab	PCR(+) and CT(+)	37% (226/610)/—	—	—	—
Fang et al. [3]	Throat swab or sputum samples	PCR(+) and CT	—/71% (36/51)	—	—/98% (50/51)	—
Mardani et al. [26]	Pharyngeal swab	PCR(+)	35% (70/200)/—	—	—	—
He et al. [2]	Nasopharyngeal swab, oropharyngeal swab, endotracheal aspirate, or bronchoalveolar lavage	PCR(+) and CT(+)	—/79% (27/34)	100%((95%CI: 100%))	—/77% (26/34)	96% (95% CI: 90–100%)
Wang et al. [6]	Throat swab samples	PCR(+)	—/65% (580/888)	83% (105/126)	—/97% (580/601)	25% (105/413)
Liu et al. [13]	Nasal and pharyngeal swabs, bronchoalveolar lavage fluid, and sputum samples	PCR(+)	38% (1854/4880)/—	—	—	—
Long et al. [1]	Pharyngeal oral and nasal sampling	PCR(+)	—/83.3% (30/36)	—	—/97.2% (35/36)	—
Ai et al. [4]	Throat swab samples	PCR(+)	59% (601/1014)/—	—	88% (888/1014)/97% (580/601)	—
Guan et al. [27]	Nasal and pharyngeal swab specimens	PCR(+)	—	—	82.1% (720/877)/—	—
Bernheim et al. [10]	Bronchoalveolar lavage, endotracheal aspirate, nasopharyngeal swab, or oropharyngeal swab	PCR(+)	88% (90/102)/—	—	78% (94/121)/—	—
Bai et al. [25]	—	—	—	—	—/79.3% (Chinese); 80.5% (United States)	68.7% (Chinese); 99% (United States)

Note: all the data were obtained from the literature. The symbol “—” represents data were unavailable. The positive rate, sensitivity, and specificity are expressed as percentage. PT: positive rate; Sen: sensitivity; Spe: specificity.