Research Article
Circulating Clusterin and Osteopontin Levels in Asthma and Asthmatic Pregnancy
Table 1
Clinical data and inflammatory parameters of the four study groups (median [interquartile range]).
| | | HNP () | HP () | ANP () | AP () |
| | Age (years) | 29.5 | 34 | 35 | 31.5 |
| | Gestational age at sampling (weeks) | NA | 35 | NA | 24.5 |
| | Gestational age at delivery (weeks) | NA | 39 | NA | 38 |
| | Fetal birth weight (grams) | NA | 3240 | NA | 3250 |
| | (% of predicted) | NA | NA | 97 | 94 |
| | PEF (% of predicted) | NA | NA | 98 | 84.50 |
| | (% of predicted) | NA | NA | 118 | 105 |
| | FEF 25–75% (% of predicted) | NA | NA | 77 | 83 |
| | ACT total score | NA | NA | 24 | 22 |
| | Daily dose of ICS (beclomethasone equivalent, µg) | NA | NA | 200 | 650 |
| | Eosinophil cells (%) | 1.595 | NA | 2.420 | 2 |
| | IL-6 (pg/mL) | NA | NA | 1.795 | 1.935 |
| | CRP (mg/mL) | 3.0 | NA | 3 | 4.845 |
| | Osteopontin (ng/mL) | 2.075 | 3.037 | 2.086 | 2.693 |
| | Clusterin (µg/mL) | 108.8 | 98.80 | 109.2 | 111.7 |
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HNP: healthy nonpregnant; HP: healthy pregnant; ANP: asthmatic nonpregnant; AP: asthmatic pregnant; : forced expiratory volume in 1 second; PEF: peak expiratory flow rate; : airway resistance; : forced expiratory flow at 25–75% of forced vital capacity; ACT: asthma control test; ICS: inhaled corticosteroid; CRP: C-reactive protein; IL-6: interleukin-6; NA: not applicable. versus HNP; versus HP.
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