Suspected Spontaneous Aqueous Humor Misdirection Syndrome in a Boston Terrier

Figure 3

Histopathology images of the enucleated canine globe (OS) with hematoxylin and eosin (H&E) stain. (a) Image of the nondependent ICA demonstrating an open angle and lack of goniodysgenesis at 4x magnification, thus ruling out primary glaucoma as the cause of this patient’s glaucoma. (b) Image of the dependent ICA demonstrating an open angle, lack of goniodysgeneis, moderate lymphoplasmacytic infiltrate in the iris, ciliary body, and trabecular meshwork, and mild preiridal fibrovascular membrane (PIFM) formation, viewed at 4x magnification. This very mild degree of inflammation is incongruent with an 8 month history of uveitis-driven glaucoma, thus supporting a differential cause for this patient’s glaucoma, such as AHMS. (c) Image of the iris leaflet with scant lymphoplasmacytic infiltration and scant PIFM.

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