Case Report
A Tumultuous Course of Exogenous Testosterone by a Bodybuilder Causing a Catastrophic Hypercoagulable State in the Surgical Intensive Care Unit
Table 1
Initial hematologic studies which indicate an unremarkable coagulopathic evaluation.
| Initial hematologic labs | Reference range and units | Result |
| Hemoglobin | 13.1–17.3 g/dl | 15.0 | Hematocrit | 39–49% | 44.4 | Platelets | 150–450 × 109/L | 330 | Heparin anti-xa unfractioned | 0.30–0.70 IU/mL | 0.36 | Protime | 9.5–12.6 sec | 12.3 | Inr | 0.9–1.2 | 1.1 | Anticardiolipin IgA | 0–19.9 APL | 0.5 | Anticardiolipin IgM Ab | 0–19.9 MPL | 0.5 | Anticardiolipin IgG | 0–19.9 GPL | <1.6 | Beta-2 gp1 IgA | 0–19.9 u/mL | <0.6 | Beta-2 gp1 IgM | 0–19.9 u/mL | 0.5 | Beta-2 gp1 IgG | 0–19.9 u/mL | <1.4 | Homocysteine | 5.90–16.00 mcmol/L | 14.64 | Collagen/epinipherine | 0–179 sec | 112 | Collagen/adp | 0–114 sec | 91 | Heparin pf4 antibody (hit) | <0.4 OD | 0.168 | JAK2 exon 12 mutation detection | — | Negative. No pathogenic genetic alterations were detected in JAK2, exons 12–15. | Pnh by flow cytometry | — | No evidence of paroxysmal nocturnal hemoglobinuria detected by flow cytometry. | Factor V leiden R506Q gene mutation | | Negative. The patient does not have the Factor V leiden mutation. | Prothrombin G20210A gene mutation | | Negative. The patient does not have the prothrombin G20210A mutation. |
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