Relapsing De Novo Membranous Nephropathy

Figure 1

Renal allograft biopsy. (a) 40x hematoxylin and eosin (HE) stains with no apparent IF/TA, (b) 100x HE, (c) Periodic acid–Schiff (PAS) stain, (d) Masson trichrome stain, and (e) Methenamine silver stain. All (c)–(e) reveal thickened glomerular basement membrane and spikes. Immunohistochemistry (IHC) shows a granular IgG deposit (f), and it is negative for C4d, SV40, and PLA2R antigen.

(a)

(b)

(c)

(d)

(e)

(f)

(g)