Late-Onset Posttransplant Lymphoproliferative Disorders after Solid Organ Transplantation in Adults: A Case Series and Review of the Literature

<div>Histology and special studies from lymph node and bone marrow in Case 2. (a) H&amp;E stain (600x). Bone marrow core biopsy showing classic Reed-Sternberg cells (arrow) within a mixed inflammatory background. (b) (1-3) Immunohistochemical stains demonstrate scattered large atypical cells which are positive for CD30 (b1), PAX5—moderate (b2), and CD15—subset weak (b3), but negative for CD45, CD20, and OCT2 (not shown). (c) EBER in situ hybridization (200x) is positive in the large atypical cells. (d) Wright-Giemsa stained bone marrow aspirate smear (1000x) showing conspicuous hemophagocytosis (arrow).</div>

Case Reports in Transplantation

fig2

Figure 2

Figure 2: Late-Onset Posttransplant Lymphoproliferative Disorders after Solid Organ Transplantation in Adults: A Case Series and Review of the Literature 

Figure 2 | Late-Onset Posttransplant Lymphoproliferative Disorders after Solid Organ Transplantation in Adults: A Case Series and Review of the Literature 