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Cases | Location | Age of recipient | Gender of recipient | Type of kidney transplant | CMV serostatus recipient/donor | CMV prophylaxis | Time after transplant when CMV infection developed | Immunosuppression regimen | Induction | Antiviral medication used for treatment | IVIG dose used for treatment | Use of plasma | Outcome |
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Drachman et al. 1970 [4] | US | 28 | Male | Cadaveric | NS/ NS | NS | 5 months | Prednisone, azathioprine | None | No | No | No | Full recovery |
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Bale et al., 1980 [5] | USA | 40 | Male | Living | NS/ NS | NS | 3 months | Prednisone and 3 days of radiation | NS | No | No | No | NS |
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Donaghy et al., 1989 [6] | UK | 48 | Male | Cadaveric | D+/R− | NS | 7 weeks | Steroids, azathioprine, cyclosporine | NS | NS | NS | NS | NS |
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De Maar et al. 1999 [7] | Netherlands | 58 | Male | Cadaveric | D+/R− | NS | 3 months | Cyclosporine, mycophenolate, prednisolone | None | Ganciclovir at a dose of 5 mg/kg every 12 h for 21 days | 5 doses | No | Full recovery |
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El Sabrout et al. 2001 [8] | Texas | 44 | Male | Cadaveric | D+/R− | 2-week preemptive course of ganciclovir followed by 3 months of oral acyclovir | 2 years, 2 months | Mycophenolate mofetil, received for acute rejection of OKT3 | NS | Steroids, no improvement | No | No | Partial recovery |
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El Sabrout et al. 2001 [8] | USA | 47 | Male | Cadaveric | D+/R− | NS | ~7 years | Unknown, received for acute rejection of OKT3 | NS | IV ganciclovir 5 mg/kg × 14 days | 6 doses | No | Full recovery |
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Keithi-Reddy et al. 2007 [9] | India | 48 | Male | Cadaveric | D−/R− | NS | 3 months post | Prednisolone, cyclosporine, mycophenolate mofetil | NS | IV ganciclovir 5 mg/kg every 12 hours for 21 days | 5 doses | No | Full recovery |
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Alvarez et al. 2010 [10] | Spain | 62 | Male | Unknown | NS | NS | 2.5 months | Steroids, tacrolimus, mycophenolate mofetil | NS | IV ganciclovir | 5 doses | No | Full recovery |
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Alvarez et al. 2010 [10] | Spain | 22 | Female | Cadaveric | D+/R− | NS | 5 weeks | Steroids, tacrolimus, mycophenolate mofetil | NS | IV ganciclovir | 5 doses | 4 cycles of plasmapheresis | Full recovery |
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Papasotiriou et al. 2013 [11] | Greece | 28 | NA | Cadaveric | D+/R− | IV ganciclovirfor 2 weeks, then 3 months with valganciclovir | 190 days | Prednisone, tacrolimus, mycophenolate mofetil | Basiliximab, solumedrol | IV ganciclovir for 21 days. Then valacyclovir after 21 days. After 2 weeks, foscarnet | No IV IG | No | Had a relapse, then full recovery |
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Shaban et al. 2016 [12] | USA | 62 | Female | Cadaveric | D+/R− | Valganciclovir for 6 months | 7 months | Tacrolimus and prednisone | Basiliximab and steroids | IV ganciclovir for 21 days | 6 doses | No | Full recovery |
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