Case Report
Diagnostic Lessons from a Complex Case of Postintestinal Transplantation Enteropathy
Table 1
Diagnostic features of acute cellular intestinal allograft rejection.
| Histological [4, 5] | Endoscopic [11] | Clinical features [6] | Biochemical [7] |
| Increased apoptotic bodies in crypts2 | Oedema, erythema | Abdominal pain | Increasing faecal calprotectin levels | Crypt epithelial injury | Villous blunting | Fever & vomiting | Decreasing serum citrulline levels | Distortion of villous and crypt architecture | Loss of mucosal vascular pattern and friability | Increased output from stoma | Presence of allospecific CD154þ T cells increases risk | Mucosal ulceration1 | Mucosal ulceration1 | Septic shock1 | Presence of DSAs increases risk |
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in severe acute cellular rejection. >6 per 10 crypts.
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