Peripheral Spondyloarthritis Presenting with Fever and Severe Systemic Inflammatory Response Mimicking Infection: A Case Series and Literature Review
Table 1
Summary of patients’ presentation, laboratory results, and treatment.
Cases
Sex
Age (y)
Nationality
Fever
Presentation
Synovial fluid cell count (µl)
Laboratory results
HLA B27
Response to DMARDs/NSAIDs
1
Male
39
Bangladeshi
Yes
Three days of acute left knee arthritis
65,000
CRP = 141
Present
Methotrexate/naproxen prn
ESR = 92
WBC = 15.3
Plat = 418
2
Male
48
Palestinian
Yes
One week of acute oligoarthritis
875
CRP = 275
Absent
SSZ + infliximab
ESR = 44
WBC = 14.6
Plat = 539
3
Male
28
Bangladeshi
Yes
Two weeks of acute oligoarthritis
12,188
CRP = 278
Present
Methotrexate adalimumab
ESR = 42
WBC = 23
Plat = 486
4
Male
23
Nepalese
Yes
Ten days of acute left knee arthritis
55,375
CRP = 195
Present
Sulfasalazine
WBC = 15
Plat = 338
WBC = white blood cell, CRP = C-reactive protein, ESR = erythrocyte sedimentation rate, plat = platelets, prn = pro re nata is a Latin term that means as needed, MTX = methotrexate, and SSZ = sulfasalazin.