Case Report

Systemic Lupus Erythematosus (SLE) with Acute Nephritis, Antineutrophil Cytoplasmic Antibody- (ANCA-) Associated Vasculitis, and Thrombotic Thrombocytopenic Purpura (TTP): A Rare Case Report with Literature Review

Table 4

TTP and SLE treatments and outcomes.

AuthorAgeTreatmentOutcome

Changcharoen and Bolger [4]35 yearsPlasma exchange
Glucocorticoids
Hydroxychloroquine
Mycophenolate
Resolution of acute symptoms
Clinical and laboratory findings back to baseline
Clinical remission achieved
Bamidele et al. [5]58 yearsGlucocorticoids
Hydroxychloroquine
Resolution of TTP specific acute symptoms
Lupus exacerbation
Clinical remission status unknown
Abu-Hismeh et al. [10]34 yearsPlasma exchange
Glucocorticoids
Rituximab
Cyclophosphamide
Unresponsive to plasma exchange, glucocorticoids, and rituximab
After cyclophosphamide, achieved clinical and laboratory findings back to baseline
Clinical remission achieved
Blum and Blake [11]44 yearsPlasma exchange
Glucocorticoids
Mycophenolate
Cyclophosphamide
Hemolytic parameters nearly or completely normalized
Active inflammation markers decreased
Remained dependent on dialysis
Clinical remission achieved