Case Reports in Pulmonology / 2020 / Article / Tab 2 / Case Report
Successful Treatment for Hypercalcemia due to Cosecretion of Parathyroid Hormone-Related Protein and 1,25-Dihydroxyvitamin D3 in Non-Small-Cell Lung Cancer: A Case Report and Literature Review Table 2 Summary of cases presenting cosecretion of PTHrP and calcitriol in solid tumors.
Author Age Sex Primary tumor Histological type Tx of HCM Sx CTx RTx Course of the tumor Outcome of HCM Effective Tx of HCM Hoekman et al. [2 ] 70 F Ovarian carcinoma Adenocarcinoma Pamidronate Yes No No Resection Improvement Operation Hydrocortisone Van den Eynden et al. [3 ] 59 M Pancreatic neuroendocrine tumor Neuroendocrine tumor Pamidronate Yes Yes No Reduction Improvement Chemotherapy Zoledronic acid Shivnani et al. [4 ] 57 M Renal cell carcinoma Clear cell Pamidronate No Yes No Progression Improvement Prednisolone Prednisolone Rodriguez-Gutierrez et al. [5 ] 35 M Seminoma Seminoma Calcitonin No Yes No Reduction Improvement Chemotherapy Nemr et al. [6 ] 60 M Lung cancer Squamous Calcitonin No No No Progression No improvement None Zoledronic acid Furosemide Ogawaa 71 M Lung cancer Squamous Prednisolone No Yes No Progression Improvement Prednisolone Calcitonin
CTx: chemotherapy; HCM: hypercalcemia of malignancy; RTx: radiation therapy; Sx: surgery; Tx: treatment. a Present case.
