Case Report

Successful Treatment for Hypercalcemia due to Cosecretion of Parathyroid Hormone-Related Protein and 1,25-Dihydroxyvitamin D3 in Non-Small-Cell Lung Cancer: A Case Report and Literature Review

Table 1

Results of laboratory tests conducted on admission.

ValueReference value

Peripheral blood
 White blood cells11,900/μL3,900-9,800
 Neutrophils85.8%
 Lymphocytes8.5%
 Basophils0.5%
 Eosinophils0.8%
 Monocytes4.4%
 Hemoglobin11.8g/dL13.5-17.6
 Hematocrit36.8%39.8-51.8
 Platelets413,000/μL131,000-362,000
Blood biochemistry
 Total bilirubin0.59mg/dL0.2-1.2
 Aspartate transaminase25U/L9.0-30
 Alanine transaminase17U/L4.0-35
 Lactate dehydrogenase197U/L80-260
 Alkaline phosphatase282U/L106-345
γ-Glutamyl transpeptidase59U/L16-84
 Total protein7.5g/dL6.5-8.2
 Albumin3.2g/dL3.9-4.9
 Urea nitrogen16.4mg/dL8.0-20
 Creatinine0.94mg/dL0.6-1.1
 Sodium143mEq/L132-148
 Potassium4.2mEq/L3.6-5.0
 Chloride105mEq/L96-110
 Calcium12.3mg/dL8.2-10.2
 Phosphorus2.6mg/dL2.3-4.3
 Intact PTH7pg/mL10-65
 PTHrP11.7pmol/L<1.1
 Calcitriol105pg/mL20-40
 25-OH vitamin D316ng/mL>20
Urine
 pH5.55.0-9.0
 Occult blood(-)
 Sugar(-)
 Protein(-)
 Urea nitrogen312mg/dL650-1,300
 Creatinine69.9mg/dL50-150
 Sodium38mEq/L70-250
 Potassium37.7mEq/L25-100
 Chloride41mEq/L70-250
 Calcium22.2mg/dL50-300
 Phosphorus36.8mg/dL<500

PTH: parathyroid hormone; PTHrP: parathyroid hormone-related protein; calcitriol: 1,25-dihydroxyvitamin D3.