Case Report

Undiagnosed Chronic Granulomatous Disease, Burkholderia cepacia complex Pneumonia, and Acquired Hemophagocytic Lymphohistiocytosis: A Deadly Association

Table 1

In vitro sensitivity of the 3 types of Burkholderia cepacia complex (Bcc) isolated from sputum cultures.

Minimal inhibitory concentrations (ug/mL) and interpretation
Bcc 1Bcc 2Bcc 3

Amikacin>64 R>64 R>64 R
Aztreonam>32 R>32 R>32 R
Cefoxitin>32 R>32 R>32 R
Ceftazidime<8 S>32 R>32 R
Ceftizoxime16 I128 R>256 R
Ciprofloxacin<0.5 S>4 R>4 R
Gentamicin>16 R>16 R>16 R
Imipenem>16 R>16 R>16 R
Piperacillin128 R>256 R>256 R
Ticarcillin/clavulanate>256 R>256 R>256 R
Tobramycin>16 R>16 R>16 R
Trimethoprim/sulfamethoxazole<16 S<16 S160 R

S: susceptible; I: intermediate; R: resistant.