Acute Coronary Syndrome in Acute Myeloid Leukemia with Maturation Accompanying Megakaryocytic Differentiation

Figure 1

Features of leukemia cells ((a) gross appearance of lard-like blood clot in the aorta; (b) Giemsa-stained cytology of leukemia cells; (c) hematoxylin and eosin- (H&E-) stained histology of the bone marrow; immunostaining for MPO (d), CD34 (e), and CD117 (f)). The coagulated leukemia cells form white-colored elastic clots in the vascular space. The leukemic blasts in pleural effusion show high nuclear/cytoplasmic ratio and lack azurophilic granules. The bone marrow reveals 100% cellularity occasionally with megakaryocytic differentiation. The blasts in the bone marrow are immunoreactive for MPO, CD34, and CD117 (c-kit).

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