ALK-Positive Anaplastic Large Cell Lymphoma: A Diagnostic Dilemma for the Otolaryngologist in a Resource Poor Setting

Figure 6

(a) At low magnification, focal effacement of lymph node architecture by cohesive infiltrate of neoplastic cells, extending from the subcapsular sinuses into the paracortical region. (b) At high magnification, large pleomorphic neoplastic cells with abundant eosinophilic cytoplasm, pleomorphic nuclei, and frequent mitotic figures, including a “hallmark” cell with horseshoe-shaped nuclei (blue arrow).

(a)

(b)