Late Lung Metastasis in a Patient with a Clear Cell Chondrosarcoma: An Indication for a Life-Long Follow-Up?

Figure 3

Lung metastasis. Histology of the wedge resection of the left upper lung lobe showing a 15 mm large, well-circumscribed chondroid tumoral lesion (hematoxylin and eosin, original magnification 12x (a)). Atypical rounded cells with a centrally placed, large round nucleus and abundant clear cytoplasm (hematoxylin and eosin, original magnification 100x (b)). Presence of osteoclast-like giant cells, a chondroid matrix, and calcifications (hematoxylin and eosin, original magnification 200x (c)). Diffuse expression of the tumor cells for S100 (original magnification 200x (d)) and Podoplanin (D2-40) (original magnification 200x (e)).

(a)

(b)

(c)

(d)

(e)