Scrotal Apocrine Adenocarcinoma with Pagetoid Phenomenon and Inguinal Lymph Node Metastases

Figure 1

(a) Cribriform pattern of apocrine adenocarcinoma. Original magnification: 100, hematoxylin/eosin stain. (b) Pagetoid infiltration of the epidermis by the malignant cells which show score 3+ staining for HER 2 in the lateral margin of the resection. Magnification: 250. (c) Immunostaining for Gross Cystic Disease Fluid Protein-15 (GCDFP-15). Intense and moderate cytoplasmic staining of tumor cells. Pagetoid infiltration of the epidermis by one tumor cell (arrow). Original magnification: 100.

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