Use of Mirtazapine and Olanzapine in the Treatment of Refractory Hyperemesis Gravidarum: A Case Report and Systematic Review

Table 3

Numerical data of the 23 cases described in the literature of pregnant women with hyperemesis gravidarum treated with mirtazapine.

			Mean	Median	Minimum	Maximum	Percentiles
	Valid	Omit					25	50	75
Age (years)	22	1	30.45	31.00	20	38	28	31	34
Gestational age (weeks)	23	0	12.30	11.00	5	25	9.00	11.00	15.00
Gesta	21	2	2.48	2.00	1	6	1.0	2.0	3.5
Para	21	2	0.71	1.00	0	2	0	1.0	1.0
Abortion	21	2	0.76	0	0	4	0	0	1
Weight loss (kg)	8	15	7.60	7.00	2.5	13.0	3.500	7.000	11.825
Initial dose (mg/day)	23	0	15.3587	15	3.75	30	7.5	15	15
Effective dose (mg/day)	22	1	20.2841	15	3.75	45	15	15	30
Days for clinical improvement (days)	14	9	4.14	3	1	14	2.00	3.00	4.25
Treatment time (days)	12	11	56.50	21	2	210	6.75	21	119
Number of antiemetics	16	7	2.88	3.0	1	6	2	3	4
Gestational age at birth (weeks)	15	8	37.07	37	30	40	35	37	40
Newborn weight (grams)	8	15	2644.63	3204.50	1102	3550	1647.50	3204.50	3329.50