Anaplastic Pleomorphic Xanthoastrocytoma Presenting with Musical Hallucination

Figure 2

(a) Histologic sections showing a cellular proliferation of pleomorphic cells, some of which are multinucleated (H&E stain, 100x original magnification); lymphocytic infiltration is also seen (b); (c) neoplastic cells show eosinophilic cytoplasm and intracytoplasmic vacuoles, with mitotic figures identified (H&E stain, 400x original magnification); immunohistochemistry shows diffuse reactivity for S-100 (d), GFAP (e), and neurofilament (f); the Ki-67 proliferative index is moderately elevated (g).

(a)

(b)

(c)

(d)

(e)

(f)

(g)