Myoglobin Cast Nephropathy Diagnosed on Renal Biopsy in a Patient Treated for Malarial Infection

Figure 1

(A) Kidney biopsy showing acute tubular injury with numerous granular casts (arrows) (H&E stain, 100x). (B) PAS-stained section showing a tubule containing granular cast material (PAS, 600x). (C) Multiple myoglobin casts staining positively by immunohistochemistry (IHC-stained section, 200x). (D) Very dark acellular material within tubules corresponding to myoglobin casts (electron microscopy photomicrograph, 3000x).