A Case of TAFRO Syndrome Developed after COVID-19 Vaccination

Figure 2

Renal histological analysis. (a) There were diffuse and global endothelial cell enlargements by cytoplasmic swelling with large numbers of inflammatory cells (PAS staining, ×400). (b) Mesangiolysis. Partial dissolution of the mesangial matrix (arrowhead) (PAM staining, ×400). (c) Endothelial cell swelling (arrowhead) (PAM staining, ×400). (d) Endothelial cell swelling occluding the capillary lumen (star) with loss of fenestrations (triangle), and expansion of the subendothelial space (diamond). Fibrin deposition was observed (white arrow). (e) Expansion of the subendothelial space was observed. Immunoperoxidase staining for CD34 (f) and CD68 (g) was positive.

(a)

(b)

(c)

(d)

(e)

(f)

(g)