Case Report

Acute Kidney Injury Secondary to Necrotizing Sarcoid Granulomatosis

Table 1

Laboratory values.

Test nameResultNormal range

Hemoglobin (gm/dl)9.812.0–15.0
Total count (cells/cumm)108004000–11000
Polymorphs78.6%45%–70%
Lymphocytes8.3%25% –40%
Eosinophils3.7%1%–6%
Basophils0.2%0%–1%
Platelet count (lakhs/cumm)4.351.5–4.5
Blood urea nitrogen (mg/dl)225–21
Serum creatinine (mg/dl)2.40.60–1.10
Serum sodium (mmol/l)134136–146
Serum potassium (mmol/l)3.63.5–5.1
Serum chloride (mmol/l)98101–109
Serum bicarbonate (mmol/l)2621–31
Serum calcium (mg/dl)13.28.8–10.6
Serum phosphorus (mg/dl)4.02.5–4.5
Serum uric acid (mg/dl)11.12.6–6.0
Serum intact parathyroid hormone (IPTH) (pg/ml)6.812–88
Serum vitamin D (25OH) (ng/ml)9.9<20
Serum vitamin D3 (125OH) (ng/ml)37.619.6–54.3
Random plasma glucose (mg/dl)10970–140
Urine colourStraw yellow/clear
Urine pH6.04.6–8
Urine specific gravity1.0051.001–1.035
Urine glucoseNegativeNegative
Urine proteinNegativeNegative
Urine bilirubinNegativeNegative
Urine ketoneNegativeNegative
Urine urobilinogen (Eu/dl)0.20.2–1.0
Urine pus cells (cells/hpf)2–3<5 cells
Urine RBC (cells/hpf)Nil0–2
Urine epithelial cells (cells/hpf)2–30–4
Urine casts (cells/hpf)NilNil
Urine crystals (cells/hpf)NilNil
Urine protein creatinine ratio (mg/mmol)0.90<0.3
24 h Urine calcium (mg/day)160<250 mg/day
Urine bence jones proteinNegativeNegative
Total bilirubin (mg/dl)0.670.3–1.2
Direct bilirubin (mg/dl)0.20<0.2
SGOT (U/L)19<35
SGPT (U/L)16<35
Total protein (gm/dl)6.86.6–8.3
Albumin (gm/dl)2.83.5–5.2
Globulin (gm/dl)4.02.0–3.5
Alkaline phosphatase (U/L)28630–120
ANANegativeNegative
C3 (mg/dl)164.090–180
C4 (mg/dl)55.7010–40
PR3–ANCA by ELISA<1:40<1:40–Negative
MPO – ANCA by ELISA<1:40<1:40–Negative
FT3 (pmol/l)2.922.5–3.9
FT4 pmol/l)1.380.56–1.50
TSH (mU/L)1.6600.34–5.60
Carcino embryonic antigen (CEA) (mcg/l)1.3<3.0
Alpha feto protein (mcg/l)1.15<0.9
Angiotensin converting enzyme levels (ACE) (nmol/ml)119
HIVNonreactiveNonreactive
HBSAGNonreactiveNonreactive
HCVNonreactiveNonreactive
Peripheral smearNormocytic Normochromic Anemia