TY - JOUR A2 - Di Carlo, Paola AU - Elias, Anthony AU - Wark, Kirsty AU - Slape, Dana AU - Cook, David AU - Lee, Kenneth AU - Mckew, Genevieve PY - 2020 DA - 2020/01/16 TI - Secondary Syphilis with Eosinophilia Complicated by Severe Jarisch–Herxheimer Reaction SP - 2150314 VL - 2020 AB - It has long been acknowledged that syphilis is a disease with a diverse range of presentations. We herein describe a case of a young man who presented with fever, rash, and eosinophilia following the commencement of allopurinol, only to be diagnosed with secondary syphilis on histopathology. His treatment was complicated by a severe exacerbation of his cutaneous eruption following the commencement of penicillin, likely secondary to a Jarisch–Herxheimer reaction, an entity often overlooked by clinicians managing syphilis. SN - 2090-6625 UR - https://doi.org/10.1155/2020/2150314 DO - 10.1155/2020/2150314 JF - Case Reports in Infectious Diseases PB - Hindawi KW - ER -