Autoreactive Antibodies Associated with Castleman Disease Triad

Table 1

Autoimmune and antibody testing.

Antibody	Suggestive for	Before tumor removal	After tumor removal
Anti-nuclear antibodies	Nonspecific	Positive	Negative
Anti-cyclic citrullinated peptide	RA	Positive	Positive
Anti-double-stranded DNA	SLE	Positive	Positive
Anticentromere	Scleroderma, CREST syndrome	Negative	–
Anti-ribosome P	SLE	Negative	–
ss-A/RO	SS, SLE, RA	Negative	–
ss-B/la	SS, SLE, RA	Negative	–
Anti-smooth muscle	Autoimmune hepatitis	Negative	–
Anti-protinase-3	Autoimmune vasculitis	Negative	–
Anti-myeloperoxidase	Autoimmune vasculitis	Negative	–
Rheumatoid factor	RA	Negative	–
Anti-ribonucleoprotein	SLE, MCTD	Negative	–
Anti-Scl70	Scleroderma	Negative	–
Anti-Jo1	Myositis	Negative	–
Sjogren’s IgG	SS	Positive	Positive
Mycoplasma pneumoniae IgM	Acute infection	Positive	–
Mycoplasma pneumoniae IgG	Clearance/chronic infection	Positive	Positive
Chlamydia pneumoniae IgM	Acute infection	Negative	–
Chlamydia pneumoniae IgG	Clearance/chronic infection	Positive	Positive
HLA-B27	B27-associated diseases	Negative	–
PNP panel	Bullous pemphigoid/pemphigus vulgaris	Positive	–

RA, rheumatoid arthritis; SLE, systemic lupus erythematosus; SS, Sjogren’s syndrome; MCTD, mixed connective tissue disease; PNP, paraneoplastic pemphigus.