Omeprazole Induced Rapid Drug Reaction with Eosinophilia, Systemic Symptoms, and Cross-Reactivity in Delayed-Type Hypersensitivity Associated with Proton-Pump Inhibitors: A Case Report and Literature Review

Table 3

Clinical presentation, internal organs involvement, and laboratory abnormalities in proton pump inhibitors induced DRESS in 16 patients.

Characteristics in PPIs-induced DRESS	Percentage affected (n = 16)
Skin rash involve > 50% BSA	100
Fever	93.8
Eosinophilia	87.5
Hepatitis	68.8
Creatinine rising	43.8
Pneumonitis	18.8

Note: BSA, body surface area; DRESS, drug reaction with eosinophilia and systemic symptoms syndrome.