Omeprazole Induced Rapid Drug Reaction with Eosinophilia, Systemic Symptoms, and Cross-Reactivity in Delayed-Type Hypersensitivity Associated with Proton-Pump Inhibitors: A Case Report and Literature Review

Table 1

ELISpot results.

Allergen/drugs	Dose	SFU/10^6 PBMC
		IFN- ELISpot
Ceftriaxone	40 g/mL	0
Ceftriaxone	200 g/mL	0
Ceftriaxone + anti-PD-L1	40 g/mL	0
Ceftriaxone + anti-PD-L1	200 g/mL	0
Meropenem	40 g/mL	0
Meropenem	200 g/mL	0
Meropenem + anti-PD-L1	40 g/mL	0
Meropenem + anti-PD-L1	200 g/mL	0
Omeprazole	1 g/mL	0
Omeprazole^a	5 g/mL	8
Omeprazole + anti-PD-L1	1 g/mL	16
Omeprazole + anti-PD-L1	5 g/mL	24
PHA	5 mg/mL	3,388

Note: ^aPositive result for ELISpot activation at an omeprazole concentration of 5 g/mL.