Case Report

Limbic Encephalitis following Allogeneic Hematopoietic Stem Cell Transplantation

Table 2

Neurological complication seen after allogeneic hematopoietic stem cell transplantation.

Classified neurological complications based on etiologyDrug-related
Metabolic
Infectious
Cerebrovascular
Immune/inflammatory
CNS relapse of underlying disease
Secondary CNS malignancy
Undefined

Classified central nervous system neurological complications based on clinical diseaseFocal epileptic seizure or general epileptic seizure
Cranial neuropathy
PRES
Encephalopathy
PML
Meningoencephalitis or encephalitis
Meningitis (leukemic, infectious), cerebritis, or ventriculitis
Autoimmune encephalitis
PALE
ADEM
LETM
Optic neuritis
Short myelitis
Subarachnoid hemorrhage
TA-TMA
TIA
NHL relapse
CNS-PTLD
Cognitive impairment

PRES, posterior reversible encephalopathy syndrome, PALE, post-transplant acute limbic encephalitis, PML, progressive multifocal leukoencephalopathy, TA-TMA, transplant-associated thrombotic microangiopathy, TIA, transient ischemic attack, ADEM, acute disseminated encephalomyelitis, LETM, longitudinal extensive transverse myelitis, CNS-PTLD, central nervous system EBV-related post-transplant lymphoproliferative disorder, and NHL, non-Hodgkin lymphoma.