Sirolimus for the Treatment of Airway Obstruction due to Indolent T-Lymphoblastic Proliferation

Table 1

Diary of symptoms reported by the patient prior to the initiation of cyclosporine, 1-month post-cyclosporine, 3 and 10-months post-Sirolimus. Grades are assigned numbers 1–10, 10 being the worst and 1 being asymptomatic.

Main symptoms reported	Grades prior to immunotherapy	Grades after 1 month on cyclosporine	Grades after 3 months on sirolimus	Grades after 10 months on sirolimus
Post-nasal drainage	8	6, 7	3, 4	1, 2
Throat clearing cough	5, 6	5, 6	4	1
Mouth breathing	10	8	2	1, 2
Voice changes	8	5, 6	3	3
Swallowing problems (choking on food)	2, 3	2, 3	2, 3	1