Zinc Monotherapy as an Alternative Treatment Option for Decompensated Liver Disease due to Wilson Disease?
Table 2
Summary of improved decompensated liver disease after zinc treatment.
No
Sex
Diagnosis
Country
Treatment
Publication details
Year of publication
1
M
Decompensated liver disease with CNS
Nigeria
Zinc
Christopher I., et al.; Wilson disease in a Nigerian child: a case report; BMJ
2012
2
F
Liver disease with CNS
Nigeria
Zinc
Longe A. C., Glew R. H., Omene J. A; Wilson’s disease. Report of a case in a Nigerian; Arch neurol
1892
3
F
Decompensated liver disease
Virginia
Zinc
Vanessa D. L., Patrick G. N., and Carl L. B.; Resolution of decompensated cirrhosis from Wilson’s disease with zinc monotherapy: a potential therapeutic option; Clinical Gastroenterology and Hepatology
2006
4
M
Decompensated liver disease
Italy
Zinc
Brewer G. J., et al.; Treatment of Wilson’s disease with zinc: initial treatment studies; Clinical MED
1989
5
Twenty-two children with Wilson disease with different degree of liver disease treated and followed up for 10 years with zinc acetate, and they show liver function and symptom improvement with no complications.
J Lab Clin Med.; 145(3):139–43
2005
6
Zinc monotherapy is effective in 44 Wilson disease patients, with mild liver disease diagnosed in childhood:
Ranucci et al; Orphanet Journal of Rare Diseases, 9:41
