Hepatic Sarcoidosis Complicated with Pancreatic Adenocarcinoma

Figure 2

The biopsy demonstrates mildly distorted hepatic architecture due to marked inflammation and presence of granulomas. There is cholestasis. Many non-necrotizing epithelioid granulomas, some confluent, are seen in the portal tracts, periportally and in the lobules. Portal tracts demonstrate mild acute and chronic inflammation (in association with granulomas), bile duct damage and mild proliferation of bile ductules accompanied by neutrophils. Ceroid-laden macrophages are seen in the lobules. There is periportal fibrous expansion and focal portal-portal bridging.