Nivolumab Effective for Gastric and Lung Cancers but Not for Multiple Myeloma in a Multiple Primary Cancer Patient

Figure 2

Clinical courses of the patient after gastric and lung cancers are diagnosed. The solid line indicates serum IgD level. Computed tomography (CT) shows the lung nodules and stomach. At the time of appearance, a pulmonary nodule with a diameter of 20 mm is found in the upper lobe of the left lung. The tumor grew over time, and a new intrapulmonary lesion appears after DOC treatment, but after nivolumab treatment, the new lesion almost disappeared and the primary lesion reduced. The gastric cancer could not be identified by CT at the start of treatment and had not changed since then. But 16 months after, gastric cancer increased. SOX: tegafur, gimeracil, oteracil potassium (TS-1), and oxaliplatin; DOC: docetaxel; Niv: nivolumab; Ld: lenalidomide and dexamethasone; DLd: daratumumab, lenalidomide, and dexamethasone, CEA: carcinoembryonic antigen.