A Rare Presentation of In Situ Mantle Cell Lymphoma and Follicular Lymphoma: A Case Report and Review of the Literature

Table 3

Clinical features, follow-up, and management in in situ MCL lesions.

Case number	Age	Site of biopsy	Management	Follow-up	Status	CD5	Concurrent malignancy	Ref
	Sex
1	70 M	Cervical lymph node	W&W	4 years	Overt MCL	−		[8]
2	65 F	LN	Chemotherapy	0.5 years	AND	−		[12]
3	65 M	Appendix	W&W	4 years	Overt MCL	+		[12]
4	66 M	Pelvic LN	W&W	4 years	Overt MCL	+	Prostate cancer	[12]
5	68 M	LN, mediastinal	W&W	1 year	AWD	Not tested		[12]
6	82 M	Oropharynx	W&W	3 years	AWD	+	CLL/SLL	[12]
7	82 M	Lymph node	Chemotherapy	1.5 years	AND	+	CLL/SLL	[12]
8	80 M	Inguinal LN	Chemotherapy	N/A	N/A	+	CLL/SLL	[12]
9	42 F	Cervical lymph node	W&W	1 year	Alive with no disease (AND)	−	Breast cancer	[12]
10	78 F	Lacrimal gland	Not available (NA)	NA	NA	+	NA	[12]
11	42 M	Supraclavicular LN	Radiotherapy	1.7 years	AND	−	Castleman disease	[12]
12	58 M	Intestine	Chemotherapy	1.4 years	AND	+	none	[12]
13	42 F	LN, axillary/inguinal, GIT	Chemotherapy	6 years	AND	+		[13]
14	70 F	LN, submandibular	W&W	12 years	AWD in Peripheral blood (PB)	+	Nonspecific granulomas	[14]
15	59 M	Cervical lymph node	W&W	5 years	AND	−	Papillary thyroid cancer	[15]
16	80 M	Cervical LN	Chemotherapy	1.5 years	Died	+	FL	[15]
17	65 F	Intramammary LN	Chemotherapy	5 years	AND	+	FL	[15]
18	65 M	Appendix	W&W	4 years	MCL	+	NA	[15]
19	68 M	Mediastinal LN	W&W	1 year	AND	NA	—	[15]
20	41 F	Inguinal lymph node (LN)	Watch and Wait (W&W)	19.5 years	Alive with disease (AWD)	−	none	[16]
21	72 F	Cervical lymph node	Radiotherapy	2 years	AND	+	Breast cancer	[17]
22	34 M	Left supraclavicular LN	Chemotherapy	1 month	Died	+	FL	[18]

W&W: watch and wait.
AND: alive with no disease.
AWD: alive with disease.
NA: nonavailable.
CLL: chronic lymphocytic leukemia.
SLL: small lymphocytic lymphoma.
LN: lymph node.
GIT: gastrointestinal tract.