Case Report

CML Developing Three Years after Therapy Completion in a Child with Ph(−) Pre-B-ALL

Table 1

Presence of BCR-ABL transcript in sequential Bone Marrow samples.

DateStatus of the diseaseBCR-ABL copy number

November 2008CP11700
August 2009CHR30
February 2010MMR3
July 2010CMRUN detectable

CP: chronicphase, (CHR): complete hematology remission, MMR: major molecular response, CMR: complete molecular response.