Transient Central Diabetes Insipidus after Discontinuation of Vasopressin

Table 1

Characteristics of reported cases of diabetes insipidus after vasopressin withdrawal. Defined by rise of urine volume correlating with spike in Na through normalization of the values.

Case #	Age/sex	Duration of DI (days)	Duration of vasopressin prior to DI (days)	Peak Na (mmol/L)	Relevant history	Reference
1	53/M	4	7	157	Hydrocephalus, VP shunt, SIADH, Pneumonia, Bacteremia, UTI	Kristeller (2004)
2	34/M	17	3	171	OHS, Pneumonia, Fungemia	Ramers (2005)
3	32/M	4	4	144	AAA, PFO, Mitral valve repair, Marfan’s syndrome	Peskey (2009)
4	30/F	3	2	154	Tetrapelegia, Ruptured cervical AVM	Sundar (2016)
5	54/M	11	4	179	Down syndrome; Hypothyroidism, CVA, Pneumonia	Rana (2018)
6	88/M	3	1	160	Septic shock, Hydrocephalus, VP shunt	Garrahy (2019)

VP, ventriculoperitoneal; SIADH, syndrome of inappropriate antidiuretic hormone; UTI, urinary tract infection; OHS, obesity hypoventilation syndrome; AAA, abdominal aortic aneurysm; PFO, patent foramen ovale; AVM, arteriovenous malformation; CVA, cerebrovascular accident.