Case Report
New-Onset Bullous Pemphigoid in a COVID-19 Patient
| Diagnostic | Location/type | Result | Normal value |
| Biopsy | Left flexor wrist | Epidermal keratinocyte necrosis, subepidermal vesiculation with eosinophils, gossamer stranding of the papillary dermis, subepidermal edema | <20 RU/mL (negative) | Direct immunofluorescence | Left flexor wrist | Strong linear IgG staining at the dermoepidermal junction, with weaker and focal linear C3 staining | ≥20 RU/mL (positive) | Antigen-specific serologic testing | Bullous pemphigoid 180 IgG Abs | 211.4 RU/mL | <20 RU/mL (negative) | Bullous pemphigoid 230 IgG Abs | <1.0 RU/mL | ≥20 RU/mL (positive) |
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