Case Report

Calcinosis Cutis Associated with Chronic Sclerodermoid Graft versus Host Disease: A Case and Review of the Literature

Table 1

Previous cases of calcinosis cutis associated with sclerodermoid graft versus host disease.

CaseAgeSexComorbiditiesIndication for BMTTime intervalType and distribution of calcinosis cutisBiochemistry (calcium and phosphate)

Lipshutz et al. [9]54FT2DM, peripheral neuropathy, diabetic nephropathy, hyperlipidemia, pericarditis, anxiety, and depressionAcute myelogenous leukemia11 yearsDystrophic
Left iliac spines, proximal, and distal lower legs
Calcium (N)
Phosphate (low)
Man et al. [10]60MDiabetes, HTN, CAD, gastric ulcers, and pulmonary fibrosisAcute myelogenous leukemiaN.SDystrophic
Chest wall, anterior thighs, upper limbs, andlower limbs
Serum calcium (N)
Phosphate (N.S)
Current case59MSteroid induced diabetes, pulmonary GVHD, and restrictive lung diseaseFollicular non-Hodgkin’s lymphoma12 yearsDystrophic
Trunk and bilateral upper limbs
Serum calcium (N)
Phosphate (N)

Age in years, F: female, M: male, T2DM: type 2 diabetes mellitus, HTN: hypertension, CAD: coronary artery disease, GVHD: graft versus host disease, time interval between GVHD and calcinosis cutis, N.S: not stated, N: normal.