Case Report
The Conundrum of Septic Shock Imitators in Patients with Hematologic Cancers: Case Presentation and Possible Differential Diagnoses
Table 2
Diagnostic criteria of HLH.
| (i) Molecular diagnosis consistent with HLH | Case | (ii) Or 5 of the following criteria | | (1) Fever | + | (2) Splenomegaly | + | (3) Cytopenia affecting ≥ 2 lineages | + | (a) Hemoglobin <9 g/dl | − | (b) Platelets <90.000/ml | + | (c) Neutrophils <1000/ml | + | (4) Hypertrigliceridemia and/or hypofibrinogemia | − | (a) Triglycerides >265 mg/dl | − | (b) Fibrinogen <150 mg/dl | − | (5) Hemophagocytosis in bone marrow, spleen or nodes () | + | (6) Low/absent NK cell activity | n.a. | (7) Ferritin ≥500 mcg/ml | + | (8) sCD25 (sIL2R) ≥2400 U/ml | n.a. |
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n.a: not available.
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