Case Reports in Critical Care / 2019 / Article / Tab 1 / Case Report
Acute Liver Failure as the Leading Manifestation of Spontaneous Tumour Lysis Syndrome in a Patient with NonHodgkin Lymphoma: Do Current Diagnostic Criteria of Tumour Lysis Syndrome Need Re-Evaluation? Laboratory blood tests/measuring unit Reference values Pre-ICU ICU DAY 1 ICU DAY 2 ICU DAY 3 ICU DAY 4 ICU DAY 5 ICU DAY 6 ICU DAY 7 ICU DAY 8 ICU DAY 9 ICU DAY 10 Red blood cells (×1012 /L) 3.86–5.08 5.21 4.23 4.19 4.74 4.54 4.17 4.08 3.96 3.91 4.05 3.71 Haemoglobin (g/L) 119–157 149 125 123 135 133 121 120 116 117 120 111 Haematocrit (L/L) 0.356–0.470 0.445 0.367 0.358 0.411 0.395 0.361 0.353 0.343 0.342 0.355 0.327 White blood cells (total) (×109 /L) 3.4–9.7 10.4 8.3 8.5 10.4 11 10.1 9.5 7 8.4 10.4 10.7 Platelets (×109 /L) 158–424 85 61 49 31 58 47 34 47 43 44 58 Serum glucose (mmol/L) 4.4–6.4 5.3 9.2 9.9 11.5 10.1 10.6 13.2 12.4 12.7 8.2 7.3 Urea (mmol/L) 2.8–8.3 14.6 20.1 18.1 16 19.2 14.4 16.7 13.1 11 7.9 7.8 Creatinine (umol/L) 49–90 186 112 120 102 121 95 113 73 71 65 90 Sodium (mmol/L) 137–146 137 151 147 141 140 138 142 141 139 135 135 Potassium (mmol/L) 3.9–5.1 4.9 5.8 4 4.4 3.5 3.9 4.4 4.3 4.5 4.6 4.7 Chloride (mmol/L) 97–108 102 109 108 104 104 102 103 99 99 98 99 Calcium (mmol/L) 2.14–2.53 2.04 2 2.14 2.12 2.05 2.16 2.03 1.86 1.96 1.97 1.95 Phosphate (mmol/L) 0.79–1.42 1.44 1.12 1.66 1.41 0.73 Total bilirubin (umol/L) 3–20 102 377 387 405 314 250 278 349 343 506 554 Conjugated bilirubin (umol/L) <5 74 310 332 333 164 195 228 270 271 394 448 Nonconjugated bilirubin (umol/L) 28 67 55 72 150 55 50 79 72 112 106 Urate (umol/L) 182–403 372 258 245 Aspartate transaminase (AST) (U/L) 11–38 459 141 88 57 48 46 56 71 66 70 77 Alanine aminotransferase (ALT) (U/L) 12–48 428 181 137 117 82 52 48 48 51 56 64 Alkaline phosphatase 50–142 356 228 186 199 188 151 132 139 138 Gamma-glutamyl transferase (GGT) (U/L) 11–55 411 130 101 109 118 108 155 239 336 490 501 Serum amylase (U/L) 40–140 78 60 57 73 74 34 26 12 Lactate dehydrogenase (LDH) (U/L) <241 786 1109 797 493 441 343 451 468 458 Ammonia (umol/L) 16–60 118.8 62.6 91.1 57.2 Lactate (mmol/L) 0.5–1.6 4.6 2 2.5 1.5 2.4 2.5 2.6 2.3 1.2 1 Procalcitonin (ug/L) <0.5—low risk of sepsis, >2— high risk of sepsis 8.69 8.89 8.1 2.43 1.79 1.37 1.09 Coagulation tests Prothrombin time (PT) 0.70–1.40 0.25 0.37 0.4 0.44 0.43 0.5 0.49 0.52 0.59 0.58 0.59 INR 2.38 1.81 1.69 1.54 1.55 1.42 1.43 1.38 1.29 1.31 1.29 APTT (s) 25.00–40.00 45.01 35.7 35.21 36 42.18 37.84 33.31 31.14 30.9 32 32.3 Fibrinogen (g/L) 1.80–4.00 1.38 3.16 2.73 2.69 2.38 2.08 2.03 1.98 2 2.2 2.2