A Case of Linezolid Toxicity Presenting as a Sepsis Mimic

Table 1

Demonstrates laboratory parameters at the time of admission and the improvement after discontinuation of linezolid.

Parameters	Day 1	Day 3	Day 5	Day 12	Day 114
Hemoglobin (g/dL)	8.4	6.6	7.9	7.9
WBC (k/µL)	16	2.9	6.7	21.1
Platelets (k/µL)	26	17	11	190
INR	8.4	1.9	1.6	1.4
Creatinine (mg/dL)	3.3	3.1	2.3	1.0
AST ( U/l)	1289	559	101	346	19
ALT (U/l)	897	688	418	669	33
LDH (units/ml)	479
Bilirubin (gm/ml)	2.1	1.3	1.4	0.9
Lactic acid (mMol/L)	12.4	6.5	4.4
Blood gas (pH)	7.06	7.4	7.38
Blood glucose (mg/dL)	54	139	207	260
Fibrinogen (mg/dL)	225