The Dynamics of Canalizing Boolean Networks

<div>Dependencies of the sample means of <svg height="11.5564pt" id="M140" style="vertical-align:-2.26807pt" version="1.1" viewbox="-0.0498162 -9.28833 25.349 11.5564" width="25.349pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M822 650H589L583 622C660 617 677 607 674 561C672 534 664 481 647 390L600 137H596L273 650H126L120 622C176 620 194 615 207 594C221 571 225 557 214 504L161 257C141 166 129 112 121 85C108 42 83 30 29 28L23 0H260L266 28C193 33 173 42 176 89C178 122 186 172 202 255L256 527H259L583 -8H612L690 390C708 481 720 535 728 558C744 603 756 619 816 622L822 650Z"></path></g><g transform="matrix(.013,0,0,-0.013,10.91,0)"><path d="M300 -147C201 -63 143 98 143 270S200 602 300 686L282 710C136 610 70 450 70 271V270C70 89 136 -72 282 -170L300 -147Z"></path></g><g transform="matrix(.013,0,0,-0.013,15.408,0)"><path d="M52 442L22 406L27 394H92V108C92 45 88 39 30 32V0H302V32C227 39 220 45 220 108V394H321C335 401 339 431 335 442H220L218 477C214 562 214 597 220 616C224 631 233 642 251 642C279 642 311 617 335 593C345 583 355 583 369 593C384 605 395 618 399 629C406 644 405 659 391 673C374 689 349 701 309 703C261 697 226 679 190 649C133 601 112 553 105 531C97 507 92 486 92 464V442H52Z"></path></g><g transform="matrix(.013,0,0,-0.013,20.664,0)"><path d="M275 270C275 450 212 609 64 710L45 686C145 604 203 442 203 270S147 -63 45 -147L64 -170C213 -68 275 89 275 270Z"></path></g></svg> and <svg height="11.5564pt" id="M141" style="vertical-align:-2.26807pt" version="1.1" viewbox="-0.0498162 -9.28833 29.5637 11.5564" width="29.5637pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M673 0V28C608 34 594 43 563 129C499 303 432 494 370 665L339 656L132 132C98 43 84 37 20 28V0H238V28C162 35 154 45 175 108C188 150 203 192 219 237H432C454 176 474 122 487 83S491 36 428 28V0H673ZM418 280H234C265 362 296 450 328 535H330L418 280Z"></path></g><g transform="matrix(.013,0,0,-0.013,8.944,0)"><path d="M409 504C401 567 396 607 392 642C354 654 312 665 266 665C137 665 60 583 60 487C60 374 161 325 225 290C300 250 355 215 355 141C355 68 311 21 235 21C131 21 86 122 71 183L41 176C48 128 61 42 68 21C78 16 93 8 118 0C142 -7 175 -15 216 -15C349 -15 438 69 438 174C438 287 344 333 265 374C186 414 138 449 138 522C138 576 172 631 249 631C336 631 363 562 380 499L409 504Z"></path></g><g transform="matrix(.013,0,0,-0.013,15.163,0)"><path d="M300 -147C201 -63 143 98 143 270S200 602 300 686L282 710C136 610 70 450 70 271V270C70 89 136 -72 282 -170L300 -147Z"></path></g><g transform="matrix(.013,0,0,-0.013,19.661,0)"><path d="M52 442L22 406L27 394H92V108C92 45 88 39 30 32V0H302V32C227 39 220 45 220 108V394H321C335 401 339 431 335 442H220L218 477C214 562 214 597 220 616C224 631 233 642 251 642C279 642 311 617 335 593C345 583 355 583 369 593C384 605 395 618 399 629C406 644 405 659 391 673C374 689 349 701 309 703C261 697 226 679 190 649C133 601 112 553 105 531C97 507 92 486 92 464V442H52Z"></path></g><g transform="matrix(.013,0,0,-0.013,24.916,0)"><path d="M275 270C275 450 212 609 64 710L45 686C145 604 203 442 203 270S147 -63 45 -147L64 -170C213 -68 275 89 275 270Z"></path></g></svg> on the canalizing depth. (a) The number of attractors <span class="nowrap"><svg height="11.5564pt" id="M142" style="vertical-align:-2.26807pt" version="1.1" viewbox="-0.0498162 -9.28833 25.349 11.5564" width="25.349pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M822 650H589L583 622C660 617 677 607 674 561C672 534 664 481 647 390L600 137H596L273 650H126L120 622C176 620 194 615 207 594C221 571 225 557 214 504L161 257C141 166 129 112 121 85C108 42 83 30 29 28L23 0H260L266 28C193 33 173 42 176 89C178 122 186 172 202 255L256 527H259L583 -8H612L690 390C708 481 720 535 728 558C744 603 756 619 816 622L822 650Z"></path></g><g transform="matrix(.013,0,0,-0.013,10.91,0)"><path d="M300 -147C201 -63 143 98 143 270S200 602 300 686L282 710C136 610 70 450 70 271V270C70 89 136 -72 282 -170L300 -147Z"></path></g><g transform="matrix(.013,0,0,-0.013,15.408,0)"><path d="M52 442L22 406L27 394H92V108C92 45 88 39 30 32V0H302V32C227 39 220 45 220 108V394H321C335 401 339 431 335 442H220L218 477C214 562 214 597 220 616C224 631 233 642 251 642C279 642 311 617 335 593C345 583 355 583 369 593C384 605 395 618 399 629C406 644 405 659 391 673C374 689 349 701 309 703C261 697 226 679 190 649C133 601 112 553 105 531C97 507 92 486 92 464V442H52Z"></path></g><g transform="matrix(.013,0,0,-0.013,20.664,0)"><path d="M275 270C275 450 212 609 64 710L45 686C145 604 203 442 203 270S147 -63 45 -147L64 -170C213 -68 275 89 275 270Z"></path></g></svg>.</span> (b) Average size of an attractor <span class="nowrap"><svg height="11.5564pt" id="M143" style="vertical-align:-2.26807pt" version="1.1" viewbox="-0.0498162 -9.28833 29.5637 11.5564" width="29.5637pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M673 0V28C608 34 594 43 563 129C499 303 432 494 370 665L339 656L132 132C98 43 84 37 20 28V0H238V28C162 35 154 45 175 108C188 150 203 192 219 237H432C454 176 474 122 487 83S491 36 428 28V0H673ZM418 280H234C265 362 296 450 328 535H330L418 280Z"></path></g><g transform="matrix(.013,0,0,-0.013,8.944,0)"><path d="M409 504C401 567 396 607 392 642C354 654 312 665 266 665C137 665 60 583 60 487C60 374 161 325 225 290C300 250 355 215 355 141C355 68 311 21 235 21C131 21 86 122 71 183L41 176C48 128 61 42 68 21C78 16 93 8 118 0C142 -7 175 -15 216 -15C349 -15 438 69 438 174C438 287 344 333 265 374C186 414 138 449 138 522C138 576 172 631 249 631C336 631 363 562 380 499L409 504Z"></path></g><g transform="matrix(.013,0,0,-0.013,15.163,0)"><path d="M300 -147C201 -63 143 98 143 270S200 602 300 686L282 710C136 610 70 450 70 271V270C70 89 136 -72 282 -170L300 -147Z"></path></g><g transform="matrix(.013,0,0,-0.013,19.661,0)"><path d="M52 442L22 406L27 394H92V108C92 45 88 39 30 32V0H302V32C227 39 220 45 220 108V394H321C335 401 339 431 335 442H220L218 477C214 562 214 597 220 616C224 631 233 642 251 642C279 642 311 617 335 593C345 583 355 583 369 593C384 605 395 618 399 629C406 644 405 659 391 673C374 689 349 701 309 703C261 697 226 679 190 649C133 601 112 553 105 531C97 507 92 486 92 464V442H52Z"></path></g><g transform="matrix(.013,0,0,-0.013,24.916,0)"><path d="M275 270C275 450 212 609 64 710L45 686C145 604 203 442 203 270S147 -63 45 -147L64 -170C213 -68 275 89 275 270Z"></path></g></svg>.</span></div>

Complexity

The Dynamics of Canalizing Boolean Networks

Figure 1