Computational and Mathematical Methods in Medicine

Phage Display Informatics


Publishing date
12 Jul 2013
Status
Published
Submission deadline
12 Apr 2013

Lead Editor

1Center of Bioinformatics, University of Electronic Science and Technology of China, Chengdu, China

2Department of Chemistry and Alberta Glycomics Centre, University of Alberta, Edmonton, AB, Canada

3National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun, China


Phage Display Informatics

Description

Phage display is an efficient laboratory technique that can be used to construct and screen combinatorial libraries of peptides and proteins displayed on the surface of bacteriophage. This technique has made a great impact on modern medicine. It has been widely used for epitope mapping, analysis of protein-protein interactions, prediction of drug target, and identification of enzyme substrates and inhibitors. Some antibodies and peptides derived from phage display technology have been developed into new drugs approved by FDA; others have shown promise for the development of diagnostics, vaccines, and the targeted delivery of therapeutics. In recent years, computational and mathematical methods play an increasingly important role in the translational medicine study using phage display.

The main focus of this special issue will be on the bioinformatics resources, models, algorithms, and programs of phage display and their applications in all fields, especially in medicine. The special issue will become an international forum for theoretical and experimental researchers using phage display technology. Potential topics include, but are not limited to:

  • Databases and benchmarks for phages, phage libraries, phage antibodies, and phage peptides
  • Mathematical models for designing phage libraries and biopanning
  • Methods for deep sequencing analysis of phage libraries and biopanning process
  • Data visualization tools, algorithms, and programs for phage display analysis
  • Computational methods for cleaning phage display data
  • Application of phage display technique to medicine
  • Application of phage display techniques to other fields

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/cmmm/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/cmmm/pdi/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 698395
  • - Editorial

Phage Display Informatics

Jian Huang | Ratmir Derda | Yanxin Huang
  • Special Issue
  • - Volume 2013
  • - Article ID 491612
  • - Research Article

Error Analysis of Deep Sequencing of Phage Libraries: Peptides Censored in Sequencing

Wadim L. Matochko | Ratmir Derda
  • Special Issue
  • - Volume 2013
  • - Article ID 943636
  • - Review Article

Bioinformatics Resources and Tools for Conformational B-Cell Epitope Prediction

Pingping Sun | Haixu Ju | ... | Yuxin Li
  • Special Issue
  • - Volume 2013
  • - Article ID 983829
  • - Research Article

Epitope Mapping of Metuximab on CD147 Using Phage Display and Molecular Docking

Bifang He | Canquan Mao | ... | Jian Huang
  • Special Issue
  • - Volume 2013
  • - Article ID 470390
  • - Research Article

Uses of Phage Display in Agriculture: Sequence Analysis and Comparative Modeling of Late Embryogenesis Abundant Client Proteins Suggest Protein-Nucleic Acid Binding Functionality

Rekha Kushwaha | A. Bruce Downie | Christina M. Payne
  • Special Issue
  • - Volume 2013
  • - Article ID 530696
  • - Research Article

Naïve Bayes Classifier with Feature Selection to Identify Phage Virion Proteins

Peng-Mian Feng | Hui Ding | ... | Hao Lin
  • Special Issue
  • - Volume 2013
  • - Article ID 653759
  • - Review Article

Uses of Phage Display in Agriculture: A Review of Food-Related Protein-Protein Interactions Discovered by Biopanning over Diverse Baits

Rekha Kushwaha | Christina M. Payne | A. Bruce Downie

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