Research Article

Differentiation of Recurrence from Radiation Necrosis in Gliomas Based on the Radiomics of Combinational Features and Multimodality MRI Images

Table 5

Comparison of the classifying results of glioma necrosis versus recurrence.

YearTypeRecurrence/necrosisAUCSeSpAcc

Tsuyuguchi et al. [38]2004PET6/51.000.60.82
Ozsunar et al. [39]2010PET/MRI (DSCE-CBV, and ASL)28/70.94
Rani et al. [1]2018SPECT/MRI (T1, T2, FLAIR, and DWI)18/100.920.92
Takenaka et al. [40]2014PET34/160.9250.9120.875
Jena et al. [41]2016PET/MRI (FLAIR, T2, DWI, MRS, and EPI)19/70.97
Jena et al. [42]2017PET/MRI (T1, T2, FLAIR, DWI, PWI/EPI, and MRS)25/100.935
Fusion AlexNetMRI (T1, T2, T1C, and FLAIR)35/160.99820.99410.97550.9786

Se: sensitivity; Sp: specificity; Acc: accuracy; DSCE-CBV: dynamic susceptibility contrast-enhanced cerebral blood volume; ASL: arterial spin-labeled; DWI: diffusion-weighted imaging; EPI: perfusion EPI; PWI: perfusion-weighted imaging; MRS: magnetic resonance spectroscopy.