Research Article

The Role of the Innate Immune System in Oncolytic Virotherapy

Table 1

Parameters and their values.

Parameters Description Values Dimensions

Tumor growth rate2 × 10−21/h
Density of tumor cells106cells/mm3
Infection rate of the virus 7/10 × 10−9mm3/h virus
Immune killing rate of infected tumor cells2 × 10−8mm3/h immune cell
Death rate of infected tumor cells 1/181/h
Burst size of free virus50viruses/cell
Immune killing rate of virus 10−8mm3/h immune cell
Clearance rate of the virus 2.5 × 10−21/h
Stimulation rate of the virus by infected cells 5.6 × 10−7mm3/h infected cell
Immune clearance rate 20 × 10−8mm3/h cell