Research Article
The Role of the Innate Immune System in Oncolytic Virotherapy
Table 1
Parameters and their values.
| Parameters | Description | Values | Dimensions |
| | Tumor growth rate | 2 × 10−2 | 1/h | | Density of tumor cells | 106 | cells/mm3 | | Infection rate of the virus | 7/10 × 10−9 | mm3/h virus | | Immune killing rate of infected tumor cells | 2 × 10−8 | mm3/h immune cell | | Death rate of infected tumor cells | 1/18 | 1/h | | Burst size of free virus | 50 | viruses/cell | | Immune killing rate of virus | 10−8 | mm3/h immune cell | | Clearance rate of the virus | 2.5 × 10−2 | 1/h | | Stimulation rate of the virus by infected cells | 5.6 × 10−7 | mm3/h infected cell | | Immune clearance rate | 20 × 10−8 | mm3/h cell |
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