Research Article
Investigating Mutations to Reduce Huntingtin Aggregation by Increasing Htt-N-Terminal Stability and Weakening Interactions with PolyQ Domain
Algorithm 2
Generating
for
-point mutations.
(1) procedure ESTIMATEDELTAE(, , , ) | (2) List(“ARNDCQEGHILKMFPSTWYV") | (3) Table //for each element in Results | (4) | (5) Tuples | (6) for () tuples in do | (7) for in do | (8) for in do | (9) | (10) for in do | (11) mutate(, , ) | (12) | (13) | (14) end for | (15) | (16) end for | (17) end for | (18) end for | (19) //Sort on second element ascending | (20) return | (21) end procedure |
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