Quantitative Measurements in 3-Dimensional Datasets of Mouse Lymph Nodes Resolve Organ-Wide Functional Dependencies

Figure 3

Histograms of the distances from the DCs to the center of the PLN. (a) and (c) two representative wt-PLNs, (b) and (d) plt-PLNs. The mean distance for the DCs in the wild type is smaller, indicating their location around the center of the PLN. In the plt/plt mutant, DCs remain close to their entry point in the periphery of the PLN. The red vertical line marks the mean distance, the dashed lines mark the standard deviation. (e) Schematic 2D depiction of the extent of the PLN (red) and DCs (cyan). The distances between the CoMs of the DCs and that of the PLN are indicated by white arrows.