Personalization of CM Injection Protocols in Coronary Computed Tomographic Angiography (People CT Trial)
Table 4
Primary and secondary outcomes for all groups on a per-patient and per-segment level.
Parameter
Group BW
Group LBW
Group CO
value BW vs. LBW
value BW vs. CO
value LBW vs. CO
No. of patients
n = 112
n = 108
n = 107
Image quality parameters per patient
Attenuation (HU)
423 ± 60
404 ± 61
413 ± 63
0.024
0.211
0.333
Scans 325–500HU (%)
83.9
84.3
86.9
0.947
0.532
0.579
Scans ≥325HU (%)
95.5
89.8
95.3
0.102
0.941
0.124
Noise
39 ± 8
39 ± 8
40 ± 9
0.844
0.332
0.451
CNR
14 ± 3
14 ± 3
14 ± 3
0.313
0.094
0.530
SNR
12 ± 3
11 ± 3
12 ± 5
0.117
0.970
0.265
Good-excellent image quality (%)
94.6
86.1
90.7
0.031
0.257
0.299
No. of segments
n = 1.599
n = 1.556
n = 1.523
Image quality parameters per segment
Scans 325–500HU (%)
67.4
67.4
66.5
1.000
0.618
0.621
Scans ≥325HU (%)
90.7
87.2
88.6
0.002
0.061
0.224
Good-excellent image quality (%)
82.9
75.1
78.6
<0.001
0.003
0.023•
Note. Values are presented as mean ± standard deviation. BW = body weight; LBW = lean body weight; CO = cardiac output; HU= Hounsfield units; CNR = contrast-to-noise ratio; SNR = signal-to-noise ratio. A significant difference was found between group BW and group LBW. A significant difference was found between group BW and group CO. •A significant difference was found between group LBW and group CO.
