^99mTc-CXCR4-L for Imaging of the Chemokine-4 Receptor Associated with Brain Tumor Invasiveness: Biokinetics, Radiation Dosimetry, and Proof of Concept in Humans

Table 3

Histopathological results (classification of the World Health Organization) and tumor/background uptake ratios (T/Bmax) evaluated with ^99mTc-CXCR4-L radiopharmaceutical in patients with suspected brain tumors.

Patient no.	Age	Reported disease	WHO grade	T/Bmax ratio
1	30	Oligodendroglioma NOS	II	1.3
2	44	Oligodendroglioma NOS	II	2.4
3	42	Glioblastoma NOS	IV	6.6
4	72	Glioblastoma NOS	IV	7
5	59	Gliosarcoma	IV	19
6	51	Metastasis of poorly differentiated malignancy	NA	5.5
7	25	Diffuse astrocytoma NOS (tumor recurrence)	II	3.9
8	25	Reactive gliosis (tumor recurrence)	NA	NA
9	34	Reactive gliosis (tumor recurrence)	NA	NA